Congenital malformations associated with a ring 4 chromosome.

Associated Risk Factors and Prevalence of Congenital Malformations in Ardabil, Iran

Introduction: Congenital anomalies are the most common cause of disability in developed and developing countries. Costs of hospitalization and treatment of congenital anomalies pose a significant burden to families and societies. The objective of the present study was to determine the associated risk factors and prevalence of congenital malformations in Ardabil, Iran. Methods: This cross-secti...

Ring Chromosome 18: A Case Report

Ring chromosomes are rare chromosomal disorders that usually appear to occur de novo. A ring chromosome forms when due to deletion both ends of chromosome fuse with each other. Depending on the amount of chromosomal deletion, the clinical manifestations may be different. So, ring 18 syndrome is characterized by severe mental growth retardation as well as microcephaly, brain and ocular malformat...

Familial occurrence of congenital malformations and ring chromosome (46,XX,Cr).

Comparative genomic hybridisation shows a partial de novo deletion 16p11.2 in a neonate with multiple congenital malformations.

Chromosome alterations, including numerical and structural chromosome rearrangements, are implicated in abnormal fetal development and congenital malformations. At least 50% of all first trimester spontaneous abortions are cytogenetically abnormal and about 6% of all postnatal congenital malformations are related to visible cytogenetic alterations detected by conventional G banding. 2 These per...

O-26: Comparison of Congenital Malformation of Infants Conceived by Assisted Reproductive Techniques versus Infants with Natural Conception in Tehran

Background: In many countries, 1% to 3% of newborn infants are conceived by Assisted Reproductive Techniques (ART). Despite the success of ART, there is concern about the risk of congenital malformations among these infants. We report our experience to determine whether use of ART is associated with an increase in major congenital malformations or adverse pregnancy outcomes Materials and Method...